Enjoy a guided tour of the Vatican’s Museums and Sistine Chapel. Built by connecting portions of the old Papal residence with newer structures, the museum houses a world-renowned collection of art and antiquities. Michelangelo painted the ceiling of the Sistine Chapel between 1508 and 1512, and later painted The Last Judgment between 1535 and 1541 for Popes Clement VII and Paul III. The primary function of the chapel is the Papal Conclave, providing the place where the College of Cardinals of the church gathers to elect a new pope. Then, walk through St. Peter’s Basilica and celebrate Mass here. The present structure, completed in 1590, was built over the Byzantine and Middle Ages structures that marked the tomb of Saint Peter. There are more than 100 tombs within the basilica, including, most recently, Saint John Paul II. Finish the day at the Pantheon, built by Marcus Agrippa during the reign of Augustus (27 BC to 14 AD). Emperor Hadrian rebuilt it around 126 AD. The building was given to Pope Boniface IV who converted it into a church - Saint Mary and the Martyrs (Santa Maria Rotunda). Mass continues to be celebrated here. Enjoy a visit to the Forum and the Colosseum, once the heart of ancient Rome and a place of martyrdom for the early saints. You will explore the romance of Rome as you stop at the famous Trevi Fountain. Legend says those who toss a coin into the fountain will one day return to Rome to toss another into the waters of Trevi. Return to your hotel for overnight. Dinner is on your own this evening. (B)

This morning begins another day of pilgrimage at the Basilica of Saint Paul Outside the Walls. The present structure stands over the place where Constantine built the first church, which is over Saint Paul’s grave. The church features a portrait of every pope who has served the church, with the face of Pope Francis I illuminated as the present pontiff. Step beneath the surface into the Catacombs of Callixtus, built along the Appian Way. Here, 16 popes from the 2nd through 4th centuries were interred, though they had been removed to various churches over the centuries. San Sebastian Outside the Walls is another of the seven pilgrimage churches built over the Catacombs of Saint Sebastian. The remains of Peter and Paul were temporarily protected here during the Valerian Persecution of 258. Our seventh and final pilgrimage stop is the Basilica of the Holy Cross in Jerusalem. Saint Helena brought Passion relics here, and the floor was covered with soil from Jerusalem. Relics here include Thomas's index finger that touched Christ's wounds after His resurrection and a piece of the Good Thief’s Cross. Those who want to complete the seven-church pilgrimage, as Saint John Paul II declared in 2000, can continue with one more stop at the Shrine of Our Lady of Divine Love. Here, a pilgrim pursued by dogs appealed to Our Lady, and she intervened for his safety. Pilgrims began to frequent the site, and a chapel was built here in 1745. Celebrate Mass in one of the churches. Dinner is on your own this evening unless you choose the optional Opera Dinner option in Rome ($ more). (B)

Enjoy a day to explore, shop and taste Rome on your own. Or purchase the optional Pompeii Day Excursion ($125 extra). Dinner is on your own this evening. (B)